Volume 48S Number 1

Volume 48S Number 2

Volume 48S Number 2

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Some materials on drug therapy of normotensive glaucoma, taking into account the level of blood pressure

A.A. Yusupov^a*, A.V. Vasilenko^b, F.M. Khamidova^c

 
ABSTRACT:     The southwestern region of Uzbekistan provides unique opportunities for observation of patients with low pressure glaucoma due to the presence of a large number of hypotensive patients in the general population. This work contains an analysis of our own clinical observations of 42 patients (84 eyes). Monitoring of the main visual functions, the magnitude of the ophthalmotonus and the state of the optic disc (according to optical coherence tomography) was carried out. Under the influence of local antihypertensive, general neuroprotective and angiotropic complex therapy in terms of up to 8 years, it was possible to stabilize decreasing of visual acuity in 46 eyes (58.3%). The visual field did not worsen in 28 eyes (33.3%), and even slightly improved in 26 eyes (30.9%). As a result of antihypertensive therapy, ophthalmotonus decreased by an average of 2.3 ± 0.7 mm Hg in 51 eyes. With repeatedly measurements of the excavation area, it turned out to be equal to an average of 1.17 ± 0.38, in later periods it expanded to 1.38 ± 0.41 mm. Unfortunately, its reverse development was not observed. Arterial hypotension is a negative factor aggravating the decay of visual functions in glaucoma.

* Corresponding author, E-mail: eyeclinic@mail.ru

Received 7 Jan 2021, Accepted 28 Apr 2022