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Volume 48S Number 2

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Modern concepts on the etiopatogenesis of background and precancer diseases of the cervix

Muhkhayohon Tukhtasinovna Khamdamovа^a, Munira Muroтovna Baratova^b  

 
ABSTRACT:     The article is devoted to the modern understanding of the etiopathogenesis of background and precancerous diseases of the cervix. The most important role in the occurrence of background and precancerous diseases of the cervix is played by environmental factors, i.e. exogenous and modifying factors, which may include trauma, inflammation, viral infection. The purpose of the study. To increase the effectiveness of the treatment of background and precancerous diseases of the cervix by photodynamic therapy. In accordance with the purpose and objectives of our study, 82 women with background and precancerous diseases of the cervix were examined and treated. The studies were conducted at the clinical base of the Department of Obstetrics and Gynecology of the Medical Faculty of the Bukhara Medical Institute named after Abu Ali Ibn Sina from 2018 to 2020 in the gynecological department of the regional perinatal center. In the analysis of gynecological morbidity, the role of hormonal and inflammatory-infectious diseases of the external and internal genitalia in the occurrence of background diseases of the cervix is noted. The study of the duration of the course of background and precancerous diseases of the cervix showed that only 19 (23.2%) of the examined women had cervical pathology detected for the first time. In 63 (76.8%) - cervical pathology lasts from 5 months to 4 years. Thus, the results of our examination allow us to conclude that PDT is a promising highly effective method of treating cervical pathology. This method provides selective death of pathological tissue, due to the selective accumulation of FS in the latter.

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Received 6 Jan 2021, Accepted 27 Apr 2022