Volume 48S Number 1

Volume 48S Number 2

Volume 48S Number 2

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Incidence and risk factors for congenital heart disease

 Guzaliya Khasanova^a*

 
ABSTRACT:      Congenital heart defects are one of the most common congenital anomalies in children (30% of all congenital malformations); they are the third most common after congenital pathology of the musculoskeletal system and central nervous system. In this regard, it was of interest to study the most likely risk factors for the formation of congenital heart defects in children. Purpose of the study. To study the risk factors for the formation of congenital heart defects in children based on an analytical review of medical records - 56 children with congenital heart defects were hospitalized in the cardiology department of the National Children's Medical Center of the Republic of Uzbekistan. Materials and methods. Analytical review of medical documentation (56 patients with congenital heart defects hospitalized in the cardiology department of the National Children's Medical Center of the Republic of Uzbekistan. The control group consisted of 32 children without pathology of the cardiovascular system. Results. Leading risk factors were identified: anemia (48.5%), chronic placental insufficiency (38%), threatened miscarriage (32.7%), toxicosis of the first half of pregnancy (22.3%) and acute viral infection in the early stages of pregnancy (21.3%). Conclusion. The risk of developing congenital heart defects in many cases is due to a combination of hereditary predisposition with a multilateral pathological influence of internal and external environmental factors, the simultaneity of their impact, as well as the duration of exposure to the damaging factor, the number of damaging factors and the simultaneity of their effects.

* Corresponding author, E-mail:

Received 28 Aug 2022, Accepted 22 Nov 2022