Research articles

ScienceAsia 48 (2022): 899-905 |doi: 10.2307/ scienceasia899-905.2022.SA2166

To study the features of extrapulmonary manifestations of helicobacter pylori infection in school-age children with chronic
gastroduodenal pathology

N. Kh. Khudayberganovaa*, I.M. Akhmedovab, A.A. Eshmurzaevaa, M.M. Azimovaa, M.V. Sibirkinaa, X.M. Marufhanova

 
ABSTRACT:     The peculiarity of the manifestations of helicobacter pylori infection in school-age children with chronic gastroduodenal pathology has been studied. 76 children aged from 7 to 17years were analyzed, making up the first group of subjects with Helicobacter pylori-associated gastroduodenal pathology. A control group (the second group) of 30 children with chronic gastroduodenal pathology unrelated to Helicobacter pylori of a similar age was compiled. It was found that with the joint course of diseases, the duration of the history of the manifestation of symptoms of dyspepsia increases with the presence of Helicobacter pylori infection. Symptoms are recorded - a decrease in appetite and a tendency to constipation, many times more often - 11.6 times in the first group and 5.3 times in the second group, respectively. There was more intense abdominal pain in the first group of children studied, the second control group was characterized by less intense pain. The inflammatory process was diagnosed in 70 (92.1%) patients from the first group, and in 6 children of the second group with esogastroduodenoscopic (EGDS), pathological changes were not recorded. An increase in the degree of Helicobacter pylori infection accompanied by longer abdominal symptoms was revealed.

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a Department of propaedeutics of internal diseases №2 of the Tashkent Medical Academy, Tashkent, Uzbekistan
b Head of the Department of Pediatrics and Childern’s Nutrition, Center for the Development of professional Qualification of Pediatpic Medical Workers of the Ministry of Health of the Republic of Uzbekistan, Tashkent, Uzbekistan

* Corresponding author, E-mail:

Received 30 Jun 2022, Accepted 9 Oct 2022