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Volume 48S Number 2

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Microbiocinosis and nonspecific resistance of the oral cavity in chronic recurrent aphthous stomatitis

Raikhon Saidumarovna Pulatova^a*

 
ABSTRACT:     Chronic recurrent aphthous stomatitis is an infectious disease caused by a combination of environmental, micro-, and macro-organisms. HRAS is characterized by frequent recurrence of AFT on the oral mucosa (OM) and with a violation of the integrity of the epithelium, local inflammation, and severe pain. Patients of group I (49 people, 50.51%) underwent pathogenetic treatment of helminthiasis, against the background of standard treatment of HRAS. 48 patients (49.49%) of group II received standard treatment for HRAS. It was found that the degree of intestinal dysbiotic changes was also higher in the group I subjects. Thus, the normal ratio of microorganisms in the intestine was registered in 11 patients (22.91%) of group II, no such patients were registered in group I; 19 patients (39.58%) of group II and 4 patients (8.16%) of group I had a dysbiotic shift; the incidence of grade I and II dysbiosis was 13 patients (27.08%) in group II and 14 patients (28.57%) in group I, and the incidence of grade III dysbiosis in group I was 19 people (38.77%) and 5 (10.41%) patients in group II, while in group I 12 (24.48%) patients had dysbiosis of the IV degree. The incidence of dysbiotic changes in the oral cavity is higher in group I: in the oral cavity, a dysbiotic shift was noted in 16 (33.33%) patients of group II and in 5 (10.2%) patients of group I, and the incidence of dysbiosis of I-II degrees was 25 (52.08%) and 13 (26.53%) people, respectively; and grade III – in 7 (14.58%) and 28 (57.14%) patients, respectively; at the same time, in group I, 3 (6.12%) patients revealed dysbiosis of the IV degree – not registered patients of group II.

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Received 30 May 2022, Accepted 08 Sep 2022